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Wednesday, July 28, 2010

The Zamboni theory - A novel approach to multiple sclerosis

Italian physician Dr. Paolo Zamboni recently reported a link between a condition termed “chronic cerebrospinal venous insufficiency” (CCSVI) and multiple sclerosis (MS). Investigators describe CCSVI as a slowing of blood flow in which veins in the neck and upper chest are not able to efficiently remove blood from the central nervous system.

Theoretically, this is thought to create increased pressure in the veins of the brain and spinal cord, which in turn would result in damage to these areas. However, this theory is controversial amongst researchers and more studies are needed to validate this theory. Zamboni and colleagues have suggested that CCSVI may be corrected through endovascular surgery, which involves inserting a tiny balloon or stent into blocked veins in order to permit the flow of blood out of the brain and spinal cord. While both the Canadian and U.S. MS Societies are supportive of more studies, they caution that such surgery is not without risk and its benefits have not yet been demonstrated.

Although intriguing, both the theory and proposed treatment need to be further researched as much more evidence is needed.

For more information, visit the MS Society of Canada’s CCSVI FAQ or consult the MS Society of Canada’s YouTube video of their April 2010 Information Session on CCSVI.